GHK-Cu 50mg

Copper tripeptide.

Identity
Sequence: Gly-His-Lys (GHK), copper(II) complex
CAS: 89030-95-5 (Cu complex); 49557-75-7 (free GHK)
Molecular formula: C14H22CuN6O4 (GHK-Cu)
Purity: ≥99% (HPLC)
Form: sterile lyophilised powder
Presentation: 3 mL vial

Research literature
Research on GHK-Cu investigates a copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a sequence present in human plasma and in collagen. In-vitro studies in dermal-fibroblast cultures characterise its stimulation of collagen and glycosaminoglycan synthesis at picomolar-to-nanomolar concentrations. Gene-expression analyses in human cell systems further examine the tripeptide-copper complex’s modulation of pathways related to tissue remodelling, antioxidant defence, and extracellular-matrix turnover.

References

1. Maquart FX et al. (1988). Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters. PMID 3169264.
2. Pickart L, Margolina A (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences. PMID 29986520.

Documentation
Batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.

Handling (research)
Store lyophilised cold and protected from light. Reconstitute according to the researcher’s own laboratory procedure.

For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.